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Xyzal (Levocetirizine) is set to be available over the counter in the Spring of 2017.

It will be the fourth antihistamine that has changed from prescription to over the counter status.

In patients with urticaria resistant to the standard dosage of cetirizine or fexofenadine, doubling the daily dose may be effective.

In a study of 51 patients treated with cetirizine at a dosage of 10 mg once daily, 18 patients had an inadequate response and were randomized to further treatment with either cetirizine 20 mg once daily or olopatadine 5 mg twice daily.

So concludes a new study published in the current issue of Journal of Allergy and Clinical Immunology in which researchers compared 18 previous trials investigating antihistamine-caused sedation levels in 1,500 people between ages 8 and 81.With so many options, we often get asked what is the difference between products.See below for our latest question and answer regarding the difference between Xyzal & Claritin!The difference between them is really blurred." "Under some circumstances, the nonsedating formulas do cause sedation and in some cases, these sedating formulas do not," he tells Web MD."In some studies we reviewed, some people actually experienced more sedation with the newer, nonsedating formulas than with the older, sedating products.

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